Focuses On Professional Cleanroom Project And Pharmaceutical Cleanroom Equipment.
Nowadays it is not enough to simply manufacture capsule filling machine clean room workshop based on quality and reliability. Product efficiency is added as a basic foundation for its design in Suzhou Pharma Machinery Co.,Ltd.. In this regard, we use the most advanced materials and other technological tools to assist its performance developments through the production process.
Sz Pharma is a first-class brand in the international market. Our high quality products help us win many awards in the industry, which is the embodiment of our brand's strength and capital to attract customers. Our customers often say: 'I only trust your products'. This is the supreme honor to us. We firmly believe that with the explosive growth of products sales, our brand will have greater influence on the market.
Service is an essential part of our endeavor at SZ Pharma. We facilitate a team of professional designer to work out customization plan for all products, including capsule filling machine clean room workshop.
We are extraction machines company in China,With years mature manufacturing experience and Team of professional engineers and designers.Can provide various of customized service.
Products and quantity purchased by customers:150 Short Path Distillation Machine
Total project value:One Set of machine,USD 28,000
Situation:
Mr.Bob is a extractor work to extract CBD for the Cosmetics products,he want to buy one machine to purify his CBD crude oil.He want us provide a short path distillation machine with some customized service for his material.
We agreed with him and had discussed with him with the detailed parameters
First of all,he hope the machine could automatically feeding and discharge.
So we added the automatic pumps for his machine,the pumps also with adjustable valves to control the flowrate.
And because Bob’s crude oil is very sticky,so we also add a heating jacket for this feeder tank,so the oil after heating will be more liquidity.
After 10days delivery date we ship to Bob and he finally received it.
For the machine designed all with fast connection parts.so it did not take long time to install It.
Later we test it and the machine work well.Bob is very happy and thus bob saved the time to look after the machine which also saved much labor cost.
Suzhou Pharma Machinery Co.,Ltd
2021-3-2
Cleanrooms Choose Our Strengths?
Three advantages
Advantage 1:
Our company specialize in clean room and equipment construction for many years, and we have done some cases about clean room all of the world, Quality and reputation are guaranteed.
Advantage 2:
the professional team will serve you 24 hours a day. If you have any questions related to products, you can contact us at any time. Our engineers will answer them for you from the most professional point of view. Of course, it doesn't mean that only the questions related to the clean room can be asked. If you have supercritical, blister machine, tablet press and other questions, you can also contact us. Our website is www.sz-paharma.com
Advantage 3:
carefree service experience. You can wait quietly after placing an order, because you can't go abroad to guide the installation under the influence of the epidemic, but some customers are not very good at installing clean rooms, so we have optimized the installation. First, we will ask engineers to optimize every detail of your CAD 2D drawings of clean rooms, such as how many clean room panels are needed on a wall, The length of U-shaped materials and other small details will be designed in three dimensions for your clean room, and explained in three-dimensional animation according to CAD two-dimensional drawings, so as to ensure that each customer will not have unnecessary trouble due to installation
Suzhou Pharma Machinery Co.,Ltd.
2022/04/26
Birkey
General requirements for structure and decoration
The dust-free laboratory is composed of experimental area, auxiliary area and public facilities area. The architectural design should reasonably arrange all kinds of zoning rooms, so that the functional zoning is clear, the traffic is reasonable, the contact is convenient, and the mutual interference is not limited.
The laboratory with multiple combinations can adopt single channel design, double channel design, and standard unit combination design.
The structure of the laboratory should have applicability, versatility and flexibility to meet the needs of the subsequent development, renovation and expansion.
Experimental rooms involving radioactivity, pollution and personal harm and other special requirements, the building layout, maintenance structure, decoration should meet the corresponding professional and technical requirements.
The laboratory should be cleaned and disinfected regularly; ground, wall and ceiling shall be integral waterproof and dust-proof construction. The interior should reduce the protruding building fittings and open pipes; Between the wall and wall, the wall and ground, the wall and ceiling should be made of a radius of not less than 0.05m semi-rounded corner.
The interior partition wall of the laboratory should be made of light materials and assembled components, and have good observation conditions; The internal partition wall as a whole should have the characteristics of firm, heat preservation, fire prevention, moisture-proof and smooth surface.
Evaluate and control major items
1. Laboratory height
The net height of the laboratory without air conditioning system is not less than 2.8m; When the air conditioning system is set, the indoor net height shall not be less than 2.6m; Local small range is not less than 2.4m.
Ps: The net height of the special function laboratory shall be determined according to the requirements of the laboratory instrument and equipment size, installation, operation and maintenance.
2. Laboratory size
The space of the standard laboratory unit is determined by the width, arrangement and spacing of the experimental platform. The standard unit of the parallel arrangement of the experimental platform should not be less than 6.6m.
The depth of the standard laboratory unit is determined by the width of the experimental platform, the layout of the fume hood and the experimental equipment, and the depth is generally not less than 6.6m, and it is not less than 5.7m when there is no fume hood.
Ps: The space and depth of the laboratory shall be determined according to the requirements of the laboratory instrument and equipment size, installation, operation and maintenance.
3. Passageway
The passageway width of the single-sided room should not be less than 1.5m, and the passageway width of the double-sided room should not be less than 1.8m. The height of the passageway shall not be less than 2.2m. The passageway should direct the direction of the evacuation exit. When there is a height difference on the floor, it is appropriate to set up a gentle slope ramp for the passage of small carts.
4. Stairs and elevators
The width of the steps for the daily passage of personnel shall not be less than 0.28m, and the height shall not be more than 0.17m.
Experimental rooms on the second floor and above should be equipped with freight elevators. Laboratories with clean requirements can set up independent dirt elevators according to the needs of use.
5. Sanitary fixture
Sanitary facilities, changing rooms and cleaning rooms should be rationally allocated according to the needs of laboratory use.
The laboratory should be equipped with changing rooms, lockers and shoe change cabinets, and the use area per person should not be less than 0.60m². The dressing room can be arranged in a centralized, decentralized or a combination of both.
6. Sound and vibration isolation
When the environmental noise exceeds the standard, sound insulation measures should be taken for the building envelope.
Laboratories or test benches that are sensitive to noise and vibration should be kept away from noise and vibration sources, and appropriate sound and vibration isolation measures should be taken.
For laboratories that produce noise during the experiment, sound insulation and noise reduction measures should be taken to avoid interference with other functional areas of the laboratory. The independently isolated noise source laboratory shall take sound insulation and noise abatement measures and shall comply with the local noise emission limits.
Vibration isolation measures should be taken for the equipment base and pipe supports of the air conditioning room and exhaust room in the building and on the roof.
7. Utility room and plumbing space
The utility room should be near the corresponding load center.
The size, location and form of the pipeline space should be determined according to the combination of the laboratory standard unit and the utility system. Pipeline space design should meet the requirements of pipeline laying, installation, maintenance and overhaul.
PHARMA CLEAN focus on professional factory workshop/cleanroom/dust-free laboratory project. With our clean room manufacturers excellent solution, you’ll have your project in high quality design and high standard working process.
Suzhou Pharma Machinery Co.,Ltd.
2024/01/03
Tia
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Rounded corners add to the power of the clean room modular window unit and improve the appearance. The unique HPL wall pores and skin guarantees compliance with cGMP clear room standards and is the choice of major pharmaceutical companies around the world. Nicos works with you to build the modular clean room that most closely fits your pharmacy plan to be compliant with USP ‹797› and USP ‹800› guidelines.
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Introduction:
Pharmaceutical cleanrooms play a crucial role in maintaining the integrity and safety of pharmaceutical products. These controlled environments require stringent measures to prevent contamination and ensure the quality of drugs. Pass boxes, also known as pass-through chambers or hatches, are essential components in pharmaceutical cleanrooms. They facilitate the transfer of materials between different areas of the cleanroom, minimizing the risk of contamination. In this article, we will explore the role and function of pass boxes in pharmaceutical cleanroom environments and delve into their importance in maintaining a sterile and controlled manufacturing process.
1. The Purpose of Pass Boxes
Pass boxes serve as an intermediary station for the transfer of materials and products between classified areas of a cleanroom. They act as a barrier, preventing direct airflow between two adjacent areas, minimizing the potential for cross-contamination. Pass boxes are typically equipped with doors on both sides, allowing materials to be placed inside from one side and retrieved from the other side. Most pass boxes are designed to maintain positive air pressure on the pharma clean room side, ensuring that any potential contaminants are purged before the door on the cleanroom side is opened.
A pass box typically consists of a stainless steel or powder-coated frame with interlocking doors and a high-efficiency particulate air (HEPA) filtration system. The HEPA filters help in maintaining the cleanliness of the air circulating within the pass box and prevent the entry of contaminants. Some pass boxes are also equipped with ultraviolet (UV) disinfection systems, further enhancing their ability to remove bacteria and other microorganisms from the material being transferred.
2. Types of Pass Boxes
Pass boxes come in various types, each designed to cater to specific requirements and cleanroom classifications. The two main types of pass boxes are mechanical interlock and air shower.
- Mechanical Interlock Pass Boxes: These pass boxes are equipped with an interlocking mechanism that allows only one door to be opened at a time. The interlock ensures that both doors cannot be open simultaneously, preventing the direct exchange of air between the cleanroom and the adjacent area. Mechanical interlock pass boxes are commonly used in cleanrooms with lower levels of contamination control.
- Air Shower Pass Boxes: Air shower pass boxes are designed to provide an additional layer of contamination control. These pass boxes incorporate an air shower system that blows high-velocity HEPA-filtered air onto the material being transferred. The air shower removes particles and contaminants from the surface of the material, further reducing the risk of contamination. Air shower pass boxes are commonly used in cleanrooms with higher levels of contamination control, such as those in the pharmaceutical industry.
3. Advantages of Pass Boxes
Pass boxes offer several advantages that make them an indispensable component of pharmaceutical cleanrooms:
- Contamination Control: The primary advantage of pass boxes is their ability to maintain a controlled environment by minimizing the risk of cross-contamination. The interlock mechanism and HEPA filtration system ensure that contaminants are removed from the materials being transferred, preventing their entry into the cleanroom.
- Efficient Material Transfer: Pass boxes streamline the material transfer process, allowing for the efficient movement of materials between different sections of the cleanroom. They eliminate the need for personnel to enter restricted areas, reducing the chances of contamination caused by human interaction.
- Maintaining Integrity: Pass boxes play a significant role in preserving the integrity of the cleanroom by preventing disruptions in air pressure differentials. The positive pressure within the cleanroom is maintained, ensuring that contaminants are continuously pushed away from the controlled area.
- Flexibility and Customization: Pass boxes can be customized to suit specific pharma clean room requirements. They can be designed to accommodate various sizes and types of materials, ensuring compatibility with different manufacturing processes. Additionally, pass boxes can be integrated with other pharma clean room pharma machinery, such as filling machines or laminar flow cabinets, further enhancing their functionality.
4. Proper Usage and Maintenance
To ensure optimal performance and longevity, pass boxes require proper usage and regular maintenance. Here are a few guidelines to follow:
- Adhere to Standard Operating Procedures: It is essential to follow established protocols and standard operating procedures when using pass boxes. Personnel should be trained on the correct usage and cleanliness requirements of the pass boxes.
- Regular Cleaning and Disinfection: Pass boxes should be regularly cleaned and disinfected to prevent the accumulation of particles, microorganisms, and potential sources of contamination. Surfaces should be wiped down using appropriate disinfectants, and filter replacements should be performed as per the manufacturer's recommendations.
- Routine Performance Checks: Periodic performance checks should be conducted to verify the functionality of the pass boxes. This includes checking the performance of the HEPA filters, interlock systems, and any additional features such as UV disinfection. Any issues or deviations should be promptly addressed to ensure the integrity of the cleanroom environment.
Summary
Pass boxes play a crucial role in maintaining the integrity and sterility of pharmaceutical cleanroom environments. By acting as a transfer point between different sections of the cleanroom, pass boxes minimize the risk of contamination and allow for efficient material transfer. Whether it is a mechanical interlock pass box or an air shower pass box, these systems offer numerous advantages, including contamination control, efficient material transfer, and maintaining cleanroom integrity. Proper usage, regular cleaning, and routine maintenance are vital to ensure their optimal performance. By incorporating pass boxes into pharmaceutical cleanroom designs, manufacturers can ensure the highest possible standards of quality and safety in their products.