Interpretation of the structural description of the tablet press turntable punch
Granule tablet press is mainly used in rubber, plastic and its products polyolefin, PVC, coiled material and polymer blending, pigment, color masterbatch, stabilizer, stabilizer and other industries, and can also be used in rubber industry, plastic industry Manufactures and scientific research institutes are used for raw rubber plasticizing, or for rubber hot-melting and rubber pressing, rubber and compounding agent mixing, color matching and proofing, hot-melting of mixed rubber and dumbbell sheet samples, aging, Tablet compression for tensile test. Common problems and solutions of granule tablet press We have said too much about future ideas and new technologies. Now maybe it is time for us to return to the original source. The changes in the future are all based on the current situation. It is possible to talk about innovation and change only if the pharma machinery used now is well understood, so today we will briefly talk about two common problems about tablet presses and their solutions. Tablet weight out of tolerance: Refers to the difference in tablet weight exceeding the limit specified in the Pharmacopoeia 1. The particle size distribution is uneven, and the particle flow rate is different during tablet compression, resulting in uneven particle size filled into the die hole. If there are more coarse particles, the tablet will be lighter, and if there are more fine particles, the tablet will be heavier. Solution: The granules should be mixed or sieved to remove too much fine powder. 2. If there is fine powder adhering to the punch and causing hanging punch, the difference in tablet weight will be large. At this time, the lower punch is not flexible to rotate. Solution: Check, remove the die, and clean the lower punch and middle die hole. 3. The fluidity of the granules is not good, and the amount of granules flowing into the middle die hole is sometimes more and sometimes less, which causes the difference in tablet weight to be too large and exceed the limit. Solution: Re-granulate or add suitable flow aids such as micro-powder silica gel to improve the fluidity of the particles. 4. Granular layering. Solve particle stratification and reduce particle size difference. 5. Smaller tablets use larger particles of material. Solution: choose the appropriate size of particles. 6. The hopper is blocked. This phenomenon often occurs with viscous or hygroscopic drugs. The feeding hopper should be dredged, the tablet pressing environment should be kept dry, and a glidant should be added appropriately to solve the problem. 7. There is a large difference in the amount of material stored in the material, which should be controlled within 50%. 8. The feeder is unbalanced or not installed properly, resulting in uneven filling. Solution: install it in place. 9. Squeegee is uneven or poorly installed. Solution: Leveling. 10. With a forced feeder, the speed of the dial of the forced feeder does not match the speed of the turntable. Solution: adjust the same. 11. The fit between the punch and the middle die hole is not good, for example, a lot of powder is leaked between the outer periphery of the lower punch and the wall of the die hole, resulting in the occurrence of the lower punch“Astringent”Phenomenon, resulting in insufficient material filling. Solution: Replace the punch and die. 12. The length of the lower punch is different and out of tolerance, resulting in uneven filling volume. Solution: fix the difference, make the difference±5μwithin m. 13. If the lower punch is damped, the damping force adjusted by the damping screw is not good. Solution: readjust. 14. The filling track is worn or the filling mechanism is unstable. Solution: replace or stabilize. 15. In pursuit of output, the turntable rotates too fast and the filling volume is insufficient. Especially when pressing large tablets, the speed should be properly reduced to ensure sufficient filling. 16. The granule tablet press is too vibrated, the structure is loose, the assembly is unreasonable or reassembled; the setting pressure of the tablet press is too high, reduce the pressure.
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