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GMP workshop workshop mixing equipment

by:PHARMA     2022-08-24
GMP pharmaceutical cleanroom pharmaceutical cleanroom mixing equipment

Mixing is an operation in which two or more solid powders are dispersed in a mixing device to achieve a uniform state. It is a basic unit in the production of solid preparations such as tablets, granules, powders, capsules, and pills. Operation, in solid powder pharmaceuticals, for raw material configuration or production...
Text label: GMP workshop, mixing equipment, Zhongjing Global Purification

GMP workshop workshop mixing equipment


Mixing is an operation in which two or more solid powders are dispersed in a mixing device to achieve a uniform state. It is a basic unit in the production of solid preparations such as tablets, granules, powders, capsules, and pills. Operation, in solid powder pharmaceuticals, mixers are indispensable devices for raw material configuration or product standardization and homogenization; when solid particles are mixed in the mixer, there are three different forms of movement: convection, shear, and diffusion; Mixing equipment consists of two basic components, a container and a device that provides energy. Due to the different shapes, sizes and densities of solid particles, the requirements for mixing are also different. There are three common types: fixed type, rotary type, and composite type; The trough mixer is mainly composed of a machine base, a motor, a reducer, a mixing tank, a stirring paddle, and a control panel. The vertical and horizontal operation generated by the S-shaped spiral belt in the horizontal tank is used to mix the materials evenly, and the tank can be wound horizontally. The shaft rotates to facilitate unloading; the trough mixer has a simple structure and is easy to operate and maintain. The disadvantage is that the mixing intensity is small and the mixing time is long. When the particle density difference is large, the particles with large density are easy to be deposited at the bottom, so it is suitable for similar densities. materials.


Double helix cone mixer consists of the following four parts: cone, screw rod, rotating arm, transmission part, the rapid rotation of the two screw rods lift the material from bottom to top, forming two symmetrical rises along the wall The spiral material flow, the rotating arm drives the screw rod to revolve, so that the material outside the stud is mixed into the spiral material correspondingly, and the material inside and outside the center cone is continuously mixed and dislocated, mixed from the center of the cone, and flows downward. Circulation, so that the materials can be mixed evenly in a short time; the double-spiral conical mixer can be operated in a closed manner, with high mixing efficiency, easy cleaning, no dust, wide applicability, uniform mixing, low power consumption, low labor intensity, and continuous Production. V-type mixer is suitable for mixing dry powder and granular materials with good fluidity. It consists of two asymmetric cylinders. The material can flow in the vertical and horizontal directions, and the mixing uniformity is high. Vacuum suction can be used. , Work in a sealed state, no transmission mechanism inside, clean and hygienic. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for GMP workshops and GMP workshops.














The frame of the two-dimensional motion mixer is divided into upper and lower parts. The mixing container is a drum with conical ends. The rotating motor fixed on the frame and its transmission mechanism drive the material barrel around its center line. Autorotation; the swing motor on the lower frame can swing both ends of the upper frame up and down through the crank rocker mechanism, and the two ends of the material barrel also swing up and down with the upper frame. The material realizes two-cone mixing; the material barrel is equipped with a discharge guide plate, which cannot be rotated forward and reverse at will. From the direction of the discharge port, the material is mixed when it is rotated counterclockwise, and the material is discharged when it is rotated clockwise; it is similar to the V-type mixer. ratio, high mixing uniformity, large material loading coefficient, small footprint and space height, convenient feeding and discharging. In the rotary disc mixer, two different solid particles entering the rotary disc mixer fall on two high-speed rotating discs, and are scattered outward under the action of centrifugal force, and the two kinds of particles are scattered at the same time. During the process of uniform mixing, the rotating speed of the rotary disc is 1500-5400r/min, and the processing capacity is determined by the size of the rotary disc. Generally, in order to ensure the mixing ratio, it is necessary to adjust the material flow through the feeder.
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