Design and construction of GMP workshop for cosmetic production
Design and construction of GMP pharmaceutical cleanroom for cosmetic production
Cosmetics production GMP workshop requires that the total area of u200bu200bthe production, filling and packaging rooms should not be less than 100m2, the per capita floor area should not be less than 4m2, the net height of the workshop should not be less than 2.5m, and the floor of the production workshop should be flat, non-slip, wear-resistant, and impermeable to water , Easy to clean and disinfect, need...
Text label: Design and construction of cosmetic production workshop, GMP workshop decoration, Zhongjing Global purification
Design and construction of GMP workshop for cosmetic production
Cosmetics production GMP pharmaceutical cleanroom requires that the total area of u200bu200bthe production, filling and packaging rooms should not be less than 100m2, the per capita floor area should not be less than 4m2, the net height of the workshop should not be less than 2.5m, and the floor of the production workshop should be flat, non-slip, wear-resistant, and impermeable to water , Easy to clean and sterilize, the floor of the work area to be cleaned should have a slope and no water; a buffer zone should be set up before the production workshop, the passage should be spacious, and the non-blocking design should be adopted to ensure transportation and hygienic safety protection; the four walls and ceiling should be light-colored , Corrosion-resistant, heat-resistant, moisture-proof and mildew-resistant materials should be lined, and should be easy to clean and disinfect, and the height of the waterproof layer should not be less than 1.5m; the production workshop with visiting corridors should be separated from the production area by glass walls to prevent man-made pollution; The production area must be equipped with changing rooms, and there should be wardrobes, shoe racks and other changing facilities indoors, and should be equipped with running water, hand washing and disinfection facilities; cosmetics manufacturers should set up secondary changing rooms and semi-finished products storage rooms according to the needs of the product category and process. , Filling room, cleaning container storage room, dressing room and its buffer zone must have air purification or air disinfection facilities; in the production workshop using air purification device, the air inlet should be far away from the air outlet, and the height of the air inlet from the ground should not be less than 2m, and there must be no pollution sources nearby.
Cosmetics production workshops should have good ventilation facilities, suitable temperature and humidity; production workshops should have good lighting and lighting, the mixed illuminance of the working surface shall not be less than 220Iux, and the mixed illuminance of the working surface of the inspection site shall not be less than 540Iux; the quality and quantity of production water The production process requirements should be met, and the water quality should at least meet the requirements of drinking water hygiene standards; the installation of fixed equipment, circuit pipes and water pipes in the production enterprise should prevent water droplets and condensate from contaminating cosmetic containers, equipment, semi-finished products, and finished products; contact with cosmetic raw materials and semi-finished products. Equipment, tools, and pipes must be made of harmless, corrosion-resistant materials, with smooth inner walls for easy cleaning and disinfection. The more commonly used sterilization methods in cosmetic production workshops include steam sterilization, ultraviolet sterilization, and microwave sterilization; the traditional steam method only requires a well-sealed cabinet or oven structure with the ability to provide continuous steam as sterilization Place the items to be sterilized in a closed warehouse, turn on the steam source, use a fan to enhance the air circulation in the warehouse, and control the temperature to 120-130 °C for 60 minutes to achieve good sterilization effect. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for cosmetic production workshops and GMP workshops.
Microwave sterilization is a sterilization method that uses a high-frequency electromagnetic field to make the molecules in the substance polarize and move rapidly and heat up rapidly. Microwave sterilization has the advantages of high sterilization efficiency, fast speed, and no pollution after processing, so it has received extensive attention. ; Microwave sterilization is suitable for small-scale research and development of cosmetics in laboratories, and is not mature for large-scale sterilization equipment, so it is rarely used in the production process. In the cosmetic production process, the ultraviolet lamp is usually installed on the cover shell on the top of the conveyor belt to realize continuous sterilization of the products on the conveyor belt. This is a common method in the current large-scale cosmetics production line; ultraviolet disinfection is also It is a commonly used method in closed production, packaging and inspection workshops. This method has the advantages of simple installation, simple equipment requirements, controllable time, no heating, and less damage to thermally unstable substances.
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