Design and construction of aseptic powder injection workshop

Design and construction of aseptic powder injection pharmaceutical cleanroom

The bottle feeding system of the sterile dispensing powder injection workshop mainly includes a buffer turntable, a mesh belt, and a bottle feeding star wheel. Transported to the bottle transport system one by one; the bottle transport system consists of bottle transport sliders,...

Text label: Aseptic powder injection workshop, design and construction of aseptic workshop, Zhongjing Global purification

Design and construction of aseptic powder injection workshop

The bottle feeding system of the sterile dispensing powder injection pharmaceutical cleanroom mainly includes a buffer turntable, a mesh belt, and a bottle feeding star wheel. It is conveyed to the bottle transport system one by one; the bottle transport system is composed of bottle transport slider, baffle, right-angle reducer and other components, and its function is to transport the packaging materials from the turntable and the star wheel to the sub-packaging and filling section; the sub-packaging system consists of It is composed of aseptic butterfly valve, sub-packaging screw, material tube, servo star wheel, etc. The sampling waste removal system is composed of suction cup star wheel, mesh belt, waste receiving box and other components, which can reject empty bottles and unplugged bottles, or take samples. ; Bottle discharge system Bottles are fed into the discharge mesh belt through the discharge star wheel, and then into the tray or into the automatic feeding and discharging system.

Before the sub-packaging in the sterile pharmaceutical cleanroom, make sure that each sub-packaging equipment is clean, dry, and the filling volume meets the regulations before formal production; a special person will distribute the raw materials to the sub-packaging equipment, and carefully check the raw material inlet before and after feeding to prevent foreign matter from falling; A fault alarm and self-stop device should be installed in the type filling machine to prevent metal chips from friction between the screw and the funnel; the compressed air used in the airflow type filling machine should be deoiled; the proven transfer procedure transfers the material to the clean area; in B Sub-packaging is carried out in the A-level area under the background of the sub-packaging; during the sub-packaging process, the filling quantity should be checked regularly, and when the filling quantity is deviated, adjustments should be made in time: inspection of the pressing station, and instructions for controlling the pressing; Visible foreign bodies in the product; fill level monitoring. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for sterile workshops and sterile workshops.

Quality control of raw materials, including content, impurities, sterility inspection, organic residual solvent, pH, solution clarity, solution color, moisture, insoluble particles, visible foreign matter, solubility, etc. Immediately after the start of sub-packaging, it is strictly controlled in accordance with the internal control standards of the enterprise to ensure the accuracy of the dose during the sub-packaging process. The three-finger method is generally used for the inspection of the capping effect. When the size of the aluminum-plastic cap is too long or too short, the effect of the capping will be affected. The aluminum side of the vial is fully wrapped after the aluminum edge of the vial is tightly fastened; because the rubber stopper may not be pressed to the vial mouth before the freeze-dried product is capped, there is a risk of contamination of this part of the product, so it is necessary to The capping machine automatically detects and rejects, generally using the rubber stopper height detection device or the vacuum detection device in the vial to judge. Verification work of the sterile sub-packaging powder injection workshop: confirm that the sub-packaging capacity meets the design requirements, and the loading amount at different sub-packing speeds meets the internal control standards of the enterprise; ensure the stability of the loading capacity of the sub-packaging machine; Hood cleanliness determination.

SUZHOU PHARMA MACHINERY CO.,LTD. promises that we will manufature our products in accordance with the strictest quality standards.

Check out offers at PHARMA MACHINERY and read exclusive reviews on latest extraction machine CUSTOM SOLUTION SERVICES on our website.we are looking forward to creating mutual benefits with you.

extraction machine CUSTOM SOLUTION SERVICES offer a wide range of extraction machine and gave the user the choice of extraction machine, extraction machine and extraction machine.

We studied how market-leading companies are harnessing data to reshapeSUZHOU PHARMA MACHINERY CO.,LTD., and explored how they can put data to work for us in ways that create value for our own businesses.

SUZHOU PHARMA MACHINERY CO.,LTD., which contributes itself on CUSTOM SOLUTION SERVICES for creating more useful application.