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Pretreatment Of Raw And Auxiliary Materials

Pretreatment Of Raw And Auxiliary Materials

2022-01-17


Tablet is one of the most widely used dosage forms with the most varieties, the largest output at present, the traditional wet granulation process is still the mainstream process in drug production. It has the advantages of mature production process, good particle quality, high production efficiency and good compression formability. It is most widely used in the pharmaceutical industry.

 

Many customers don't know much about the pretreatment of raw and auxiliary materials when making tablet pressing. Today, I'll tell you about the pretreatment of raw and auxiliary materials.

 

Raw and auxiliary materials generally need to be crushed and screened before wet mixing and granulation production. Some unqualified phenomena often occur in the tablet pressing process, such as uneven mixing, cracking, sticking and punching or unqualified dissolution, are closely related to the insufficient crushing fineness of raw and auxiliary materials during pretreatment.

 

If the raw and auxiliary materials are flake or acicular crystals, the possibility of the above deviation will be more obvious. 80 mesh or 100 mesh screen is generally selected for crushing and screening in traditional process pretreatment. However, with the progress of equipment and raw material process, most of the raw materials selected to crush 80 mesh screen in traditional process can now pass 100 mesh screen, and the probability of the above phenomenon of fine powder after crushing 100 mesh screen is greatly reduced. Therefore, the fineness of raw and auxiliary materials passing the 100 mesh screen is gradually replacing the 80 mesh screen process.  

 

The above is today's content about the pretreatment of raw and auxiliary materialsin the next issue, I will share with you the next step of weighing and preparing granules. If you want to know more about tablet making skills, you can collect our website. We will update the content every day. At the same time, you can also click to contact us to learn more about our products.Thank you for reading.See you next time.


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Suzhou Pharma Machinery Co.,Ltd.

2022/01/12

Mia



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