The Key Factor of Clean Room - Pressure Difference

Factors affecting pressure difference control in clean room

Clean room pressure difference control is affected by a variety of factors, mainly including the following aspects:

(1) Sealing performance of clean room

The doors, Windows, walls, floors and other structures of the clean room should have good sealing performance to prevent the intrusion of external pollutants. At the same time, ventilation pipes, exhaust outlets, etc., should also be kept intact to avoid the occurrence of air leakage.

(2) Design and operation of ventilation system

Ventilation system is the core part of clean room differential pressure control. A reasonable ventilation system design should ensure that the air flow inside and outside the clean room is evenly distributed to avoid air flow dead Angle and vortex phenomenon. In addition, the operating parameters of the ventilation system should also be adjusted and optimized according to the actual situation of the clean room.

(3) Personnel activities and equipment operation

Personnel activities and equipment operation in the clean room will produce certain air disturbance and dust emission, which will have a certain impact on pressure difference control. Therefore, unnecessary activities and operations should be minimized in the clean room, and equipment should be regularly maintained and cleaned.

Clean room differential pressure control strategy

According to the influencing factors of clean room pressure difference control, the following strategies can be adopted for optimization:

(1) Improve the sealing performance of the clean room: by strengthening the tightness of the clean room structure, optimizing the design of doors and Windows, replacing sealing materials, etc., improve the sealing performance of the clean room and reduce the intrusion of external pollutants.

(2) Optimization of ventilation system design: according to the actual situation and process requirements of the clean room, reasonable design of ventilation system to ensure uniform air distribution and moderate wind speed. At the same time, the ventilation system is regularly maintained and cleaned to maintain its normal operation.

(3) Adjust the operating parameters of the ventilation system according to environmental factors such as pressure difference changes, temperature and humidity in the clean room and outside, timely adjust the operating parameters of the ventilation system, such as wind speed and air volume, so as to achieve effective control of the pressure difference.

(4) Establish a pressure difference monitoring system By installing pressure difference sensors, data collectors and other equipment, real-time monitoring of the pressure difference between the clean room and the outside, to provide data support for pressure difference control. At the same time, the establishment of pressure difference alarm mechanism, when the pressure difference exceeds the set range, timely alarm, in order to take timely measures to deal with.

Suzhou Pharma Machinery Co.,Ltd.

2025/09/24

Tia