Design and construction of clean and dust-free workshop for tea production

Tea production workshop generally includes primary and refining workshops, packaging rooms, warehouses, etc. The height, width, area and structural requirements of the processing workshop should be designed and determined according to the processing requirements of different teas; tea processing workshops , need to set up logistics import and export...
Text label: Tea production purification workshop, design and construction, tea dust-free workshop

Design and construction of clean and dust-free workshop for tea production


Tea production workshop generally includes primary and refining workshops, packaging rooms, warehouses, etc. The height, width, area and structural requirements of the processing workshop should be designed and determined according to the processing requirements of different teas; tea processing workshops , it is necessary to set up logistics import and export and personnel import and export, and requires that the logistics mouth and personnel mouth be set separately. When there is no fresh leaf raw material, finished tea and other materials in and out, only the personnel import and export are opened, and at the personnel import and export, male and female The dressing clean room modular, there should be boxes or cabinets for storing clothes and shoes in the dressing clean room modular, and hand washing and drying facilities should be set up in the passage between the dressing room and the workshop; the tea production and purification workshop should also set up a visiting passage, which is located in the Outside the main workshop, the walls of the main workshop and the main workshop can be designed into a large glass window structure to facilitate the viewing of the operation in the workshop; a special viewing channel can also be set up in the workshop, and the channel is pulled out by a fence when visiting, but visitors need to Wear work clothes as required before entering the workshop.


The window area of u200bu200bthe tea workshop should be as large as possible. Generally, the area of u200bu200bdoors and windows should account for 35% to 40% of the wall area. All doors and windows should be covered with yarn, and all entrances and holes should be protected from rodents. Facilities; workshop lighting should be based on the principle of being able to correctly identify the true color of tea leaves and products in process. Fluorescent lamps or incandescent lamps should be installed, and the illuminance should reach more than 500lx; the floor of the workshop should be smooth and free of ash; The ash is flying and the dust is large, so the tea machinery itself is required to have dehumidification and dust removal devices; the air in the workshop is required to be smooth. In addition to properly increasing the height of the workshop, a dust removal fan should be installed on the outer wall to force air circulation; For large screening and air selection, a dust removal system should be installed to improve the working environment of the workshop. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for tea production purification workshops, dust-free workshops, and tea SC workshops.














During the processing of scented tea, the flower booth should be clean and cool, with good ventilation, wide doors and windows to facilitate air convection, and air-conditioning equipment should be installed if possible; The workshop is required to be relatively sealed, so that the air is relatively still, the bay should be large, the doors and windows are convenient to open and close, and it is convenient for the planting machinery operation. In the greening workshop of oolong tea, because the shaking process will evaporate the water in the leaves, a series of chemical reactions will slowly take place in the leaves to form the unique aroma and style of oolong tea. Therefore, the greening clean room modular generally faces north and avoids direct sunlight. , The workshop should be relatively sealed, so that the air is relatively still, and if possible, automatic temperature and humidity control equipment should be installed to maintain the appropriate temperature and humidity required for greening in the workshop. Stalling and fixing workshop for green tea processing, withering workshop for processing black tea, oolong tea and other teas, fermentation and stacking workshop for processing black tea, dark tea and pressed tea, and drying workshop for all tea processing, etc. , Due to the high evaporation intensity and high humidity of tea during the processing, the height of the workshop should not be lower than 5m, and even as high as 8m in a few large tea factories. And to prevent the air circulation in the workshop.
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Tablet clean room design and installation

The production process of tablet dust-free workshop includes granulation, tableting, coating, packaging and other processes. The preparation methods can be summarized as: wet granulation and tableting, dry granulation and tableting, and direct tableting. Granulation, as the processing process of particles, is related to almost all solid preparations. The preparations may...
Text label: tablet dust-free workshop, tablet production workshop design and decoration, tablet production pharmaceutical cleanroom installation

Tablet dust-free pharmaceutical cleanroom design and installation


The production process of tablet dust-free pharmaceutical cleanroom includes granulation, tableting, coating, packaging and other processes. The preparation methods can be summarized as: wet granulation and tableting, dry granulation and tableting, and direct tableting. Granulation is the processing process of particles, which is related to almost all solid preparations. The preparations may be final products or intermediates. The granulation operation makes the particles have a certain corresponding purpose to ensure product quality and smooth production. , the granulation process can be completed in the granulator, the obtained granules should have good fluidity and compressibility, and have suitable mechanical strength, can withstand the damage of loading and unloading and mixing operations, but are pressed in the die When granulating, the granules should be broken; granulation includes wet granulation, dry granulation and spray granulation. During wet granulation, a binder is added to the drug powder, and the powder is agglomerated by the bridging or bonding effect of the binder. The preparation of granules, extrusion granulation, rotary granulation, fluidized granulation and stirring granulation, etc. belong to wet granulation. Because the surface of the granules prepared by wet method is wetted, the surface modification is better, and it has beautiful appearance, It has the advantages of strong wear resistance and good compression formability, and is widely used.


Tabletting is the core operation of tablet production, and its basic equipment is a tablet press, which places various granules or powdery materials in the die holes
, according to different structures, tablet presses can be divided into single punch tablet presses, rotary multi punch tablet presses and high-speed tablet presses. According to different special requirements, there are two-step three-step tablet presses, multi-layer tablet presses Tablet presses and press coaters, etc. The working process of the tablet press can be divided into: the punch part of the lower punch extends into the middle die hole from the lower end of the middle die hole to seal the bottom of the middle die hole; the feeder is used to fill the middle die hole; the punch of the upper punch The head part falls into the middle die hole from the upper end of the middle die hole, and goes down for a certain stroke; the upper punch lifts out of the hole, and the lower punch rises to push the tablet out of the middle die hole to complete a tableting process; the lower punch descends to the original position, ready to next fill. Various tablets have different dosage requirements. Large dosage adjustment is achieved by selecting punches with different punch diameters. In dosage control, the action principle of the feeder also has a considerable impact. For example, physical drugs rely on their own weight and freedom. When rolling into the middle die hole, the filling condition is relatively loose. If multiple forced filling methods are used, the die hole will be filled more and the filling condition will be denser. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for dust-free workshops and dust-free workshops.














Coating is a commonly used preparation process after the tableting process. The surface of the tablet is wrapped with a coating of suitable materials to isolate the tablet from the outside world. According to the different dissolution characteristics of the coating material, it is often divided into sugar-coated tablets. , film-coated tablets, enteric-coated tablets and film-controlled release tablets, etc.; coating methods include roll-on coating method, fluidized bed coating method and compression coating method; coating equipment includes common coating pan, high-efficiency coating The pot type structure of high-efficiency coating machine can be roughly divided into three types: mesh type, gap mesh type and non-porous type. The common coating pan is the most basic and most commonly used tumble coating equipment. This equipment consists of four parts: coating pan, power system, heating system and exhaust system. The work of fluidized bed coating is similar to that of fluidized spray granulation, that is, the coating liquid is sprayed on the surface of the tablet suspended in the air at a certain flow rate, and the heated air volatilizes the solvent on the surface of the tablet to form a film.
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Design and installation of clean workshop in pharmaceutical industry
The implementation of WIP manufacturing enterprises includes two aspects: software and hardware. Software is an advanced and reliable production process, strict management system, documents and quality control system; hardware is a qualified clean workshop, production environment and equipment, and hardware facilities are the basis for product production...
Text label: Design of clean pharmaceutical cleanroom for pharmaceutical industry, Design and installation of clean workshop

Design and installation of clean workshop for pharmaceutical industry


The implementation of WIP manufacturing enterprises includes two aspects: software and hardware. Software is an advanced and reliable production process, strict management system, documents and quality control system; hardware is a qualified clean workshop, production environment and equipment, and hardware facilities are the basic conditions for product production. The clean workshop facilities of product manufacturing enterprises mainly include: plant building entities (including doors and windows), roads, green lawns, and enclosure structures; production of clean workshop auxiliary public facilities, such as clean air conditioners and dust removal devices, lighting, fire sprinklers, etc. , sewer network, clean public works (such as purified water, water for injection, clean gas generation), etc. The rational design of the above clean workshops is directly related to the quality of the products.


In addition to strictly complying with the relevant regulations of GMP, the design of clean workshop facilities in the pharmaceutical industry must also comply with the relevant national policies, implement the current relevant standards and specifications, meet the requirements of practicality, safety and economy, save energy and protect environment. Under possible conditions, actively adopt advanced technology, which not only meets the needs of current production, but also considers future development; for existing building technology renovation projects, it is necessary to proceed from reality and make full use of existing resources.






As the basic hardware of product production, clean pharmaceutical cleanroom facilities are an important element of the quality system. Their location, design, construction, use and maintenance will have a significant impact on product quality. The reasonable layout of plant facilities, high-quality construction and necessary maintenance activities can provide reliable guarantees for the production and storage of products (such as clean environment, suitable temperature and humidity, etc.); it can minimize the risk of affecting product quality; At the same time, it can ensure the health and production safety of employees and provide the necessary protection for the environment. Zhongjing Global Purification can provide consulting, planning, design, construction, installation and transformation of sterile rooms and clean workshops and other supporting services.


Product production enterprises must have a clean production environment, the ground, road and transportation of the factory area should not cause pollution to the production of products; the overall layout of production, administration, living and auxiliary areas should be reasonable and should not interfere with each other. The pharmaceutical cleanroom should be reasonably arranged according to the production process and the required air cleanliness level, and the operations in the same factory room and between adjacent ones should not interfere with each other. The flow of people and logistics should follow the direction of cleanliness level from low to high, and buffer transitions should be provided for different cleanliness levels.






Industrial clean workshops should have facilities to prevent the entry of insects and other animals; when designing and constructing workshops, the ease of cleaning should be considered. The inner surface of the clean room should be flat, smooth, without cracks, with tight joints, without particles falling off, and resistant to cleaning and disinfection. The junction of the wall and the ground should be curved or other measures should be taken to reduce dust accumulation and facilitate cleaning. The production area and storage area should have space suitable for the production scale to accommodate equipment and materials, facilitate production operations, store materials, intermediate products, products to be inspected and finished products, and minimize errors and cross-contamination. Various pipes, lamps, air vents and other public facilities in the clean area should be designed and installed to avoid parts that are not easy to clean; the pipes should be less bent, the lamps should be embedded, and the upper maintenance should be carried out.
The air outlet should be flat and the interface should be sealed; the clean area should be provided with sufficient lighting according to the requirements of production; the production department with special requirements for contrast can be set up with local lighting; Replacement; set up safe entrances and exits. Staff need to pass through a relatively long sanitary passage to enter the clean room. Therefore, a passage that is conducive to evacuation must be set up in the industrial clean workshop.
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