Design of water system in clean room

Design of water system in clean room

Clean room For the purified water system, the microbial control in the water treatment process always runs through the entire treatment process. For example, if an activated carbon filter or softener is used in the system, it will be intercepted in the filter due to the adsorption of activated carbon. Organic matter on the upstream side of the filter will continue to...

Text label: clean room design, clean room construction, water system design

Design of water system in clean room

Clean room For the purified water system, the microbial control in the water treatment process always runs through the entire treatment process. For example, if an activated carbon filter or softener is used in the system, it will be intercepted in the filter due to the adsorption of activated carbon. The organic matter on the upstream side of the filter will continue to increase. If there is no corresponding sterilization measures, the activated carbon filter should be periodically disinfected to reduce the biological load on the upstream side of the activated carbon filter. After a period of use, although the activated carbon filter The function of the filter itself has not been reduced, but due to the accumulation of organic matter on its upstream side, the microbial indicators in the water after use will exceed the influent indicators before treatment; the finished water storage tanks and water distribution pipelines of purified water should be regularly Carry out microbial disinfection; work should be carried out to control and reduce microbial pollution according to the functions and characteristics of the water treatment equipment used in the purified water system for the process.

Purified water equipment should have the characteristics of no non-flowing dead water section, all equipment should have the ability to empty the remaining water inside the system, and the water outside the system will not flow back to the system to cause pollution; purified water treatment equipment and system pipelines All should have the ability to prevent contamination and regular disinfection, reduce bioburden or restore to bioburden levels. The requirements of the water for injection system are similar to those of the purified water system, and they are more strict, especially the control of microbial indicators; the main equipment in the water for injection system is distilled water machine, storage tank, sanitary water pump, valve and pipeline. The special requirements of the water for injection system are almost harsher than those of the purified water system. The main principle is to control the quality of the distilled water effluent. The distilled water machine can sterilize itself to prevent cross-contamination between the distilled water effluent and the cooling water of the distilled water machine. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for dust-free workshops and sterile workshops.

Pure steam equipment should be able to produce pure steam with the same water quality index as water for injection. On the basis of overcoming the resistance of the pipeline system, the pressure of pure steam should be able to meet the pressure of sterilization equipment or wet heat sterilization of system pipelines and temperature requirements; pure steam equipment and pipelines can be isolated from the atmosphere when not in use, and will not be polluted by microorganisms in the air; pharmaceutical water systems have various types of water according to process water requirements and specific water conditions. The system design form, no matter what kind of system design form it is, is based on the special situation of pharmaceutical water, and comprehensively designs the requirements for the preparation, storage, distribution and transportation of process water, and microbial control; the design of the purified water system can be multi-functional. These choices are related to the water quality of the source water, the process requirements of the product and other actual conditions of the enterprise. The most fundamental principle is to meet the requirements of GMP and produce purified water that meets the standards.

SUZHOU PHARMA MACHINERY CO.,LTD. also discusses implications for both research and the practice of operations in building systems to help people succeed in both the short and long run.

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