Design and construction of cosmetic purification plant
Design and construction of cosmetic purification plant
According to the air quality requirements, the production workshop should be divided into clean area, quasi-clean area and general area according to the requirements of product process environment control; general area is the functional room or area without direct exposure of raw materials, inner packaging and semi-finished products ; The quasi-clean area is raw materials, internal...
Text label: Cosmetic purification plant, production workshop design, installation and construction
Design and construction of cosmetic purification plant
According to the air quality requirements, the production workshop should be divided into clean area, quasi-clean area and general area according to the requirements of product process environment control; general area is the functional room or area without direct exposure of raw materials, inner packaging and semi-finished products ; The quasi-cleaning area is the functional room or area where raw materials, inner packaging, etc. are exposed; the cleaning area is generally the functional room or area where the semi-finished product is exposed; The air quality in the container storage room should meet the 300,000-level cleanliness requirements; in view of the different air quality requirements in different cleanliness levels, the corresponding pressure difference should be maintained between the production areas of each level. The higher the cleanliness level, the higher the air pressure. For example, a certain positive pressure difference should be maintained between the clean area and the quasi-clean area, which is mainly to ensure that the air can always flow from the high-level clean area to the low-level clean area, otherwise it is likely to cause invisible cross-contamination; cosmetic purification plant production The control of temperature, humidity and relative humidity in the workshop should also meet the requirements of the product process. The company should formulate a pharmaceutical cleanroom environment monitoring plan and monitor it regularly so as to detect problems and take corrective measures in time; the waste gas and waste generated in the production process must also be effectively controlled and properly disposed of. , so that it will not pollute the product.
Enterprises should install lighting systems that meet various operating requirements according to different production operations, and provide enough lighting to facilitate employees' daily operations. Good lighting can effectively reduce quality risks caused by insufficient light, which is very important for nighttime production operations. It is particularly important; the mixed illuminance of the working surface of the production pharmaceutical cleanroom shall not be less than 220Ix, and the mixed illuminance of the working surface of the inspection site shall not be less than 450Ix; the lighting facilities of the enterprise shall also be able to prevent pollution from cracks and fragments, or take appropriate measures to protect the product. Pest pollution is also one of the common quality problems. Good control of the production environment can effectively reduce or even eliminate the possibility of pest pollution. Enterprises should establish written and effective rodent and pest control procedures and control plans, and production workshops should be equipped with effective rodent control procedures. Facilities where pests enter and gather, such as mosquito killers, mouse traps, and mouse-blocking boards, etc., and ensure that the on-site layout is reasonable; special personnel should be installed to clean, regularly inspect and monitor these facilities to ensure good working conditions; kill The installation position of the insect lamp should ensure that the light source does not directly face the door leading to the outdoors, so as to prevent the light from attracting insect pests. At the same time, food and other baits should not be placed in the indoor mousetrap to prevent the smell from attracting outdoor insects; Records should be kept of all cleaning, inspection and monitoring of pest facilities. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for cosmetic production workshops and purification plants.
The surface of the production equipment in direct contact with the product in the cosmetic purification plant should be flat, smooth, easy to clean, corrosion-resistant and easy to disinfect. The selected lubricant and cleaning agent shall not cause pollution to the product or container; the equipment that does not meet the requirements shall be In the long-term production process, it will react with the material, or be corroded by the material, causing the dissolved substances or the surface of the equipment to peel and fall off, causing pollution to the product. Therefore, all raw materials, equipment, pipes, tools and other materials that are in direct contact with the product should be Confirmed to ensure that no chemical contamination, microbiological contamination and physical contamination are introduced. Enterprises should arrange production equipment reasonably according to the production process requirements of cosmetic purification workshops and workshop layout requirements. Enterprises can install equipment in appropriate locations according to the size of the workshop, the flow of production processes, the direction and distance of material movement, etc. The workshop area ensures the normal operation of the equipment and meets the requirements of the production process; the placement of the equipment should avoid the impact of the movement of materials and equipment, and the movement of personnel on the quality, because the frequent movement of materials by personnel will cause material pollution, and the movement of personnel will also cause workshop particles. The increase in the number will affect the air quality of the pharmaceutical cleanroom, and the frequent movement of equipment will also affect the stability of the equipment.
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