Construction of dust-free purification workshop for pharmaceutical packaging materials
Construction of dust-free purification workshop for pharmaceutical packaging materials
According to the contact relationship between the packaging and the drug, it is divided into inner packaging, middle packaging and outer packaging. The inner packaging is also called direct packaging, such as glass ampoules, plastic ampoules, vials, oral liquid bottles and other inner packaging forms. Packaging materials include plastic, glass, metal, composite materials, etc.;...
Text label: pharmaceutical packaging material clean clean room modular, pharmaceutical packaging material purification workshop, construction and decoration of pharmaceutical packaging material workshop
Construction of dust-free purification workshop for pharmaceutical packaging materials
According to the contact relationship between the packaging and the drug, it is divided into inner packaging, middle packaging and outer packaging. The inner packaging is also called direct packaging, such as glass ampoules, plastic ampoules, vials, oral liquid bottles and other inner packaging forms. Packaging materials include plastic, glass, metal, composite materials, etc.; the form of middle packaging is corrugated cardboard boxes, and the form of outer packaging is folding cartons, plastic drums, plywood drums, etc.; according to the sealing performance of packaging containers, packaging containers can be divided into airtight , Airtight and closed, airtight containers can prevent the intrusion of solid foreign bodies, airtight containers can prevent the intrusion of solid foreign bodies and liquids, and sealed containers can prevent the entry of gaseous microorganisms. There are many kinds of medicine packaging paper, the common ones are wax paper, filter paper, soluble filter paper and wrapping paper; wax paper is paper treated with low melting point paraffin, which has the characteristics of moisture resistance and oil resistance, and is usually used for packaging honey pills; most filter papers It is composed of cotton fibers, which are made by different methods according to different purposes. The material is made of fibers, so its surface has numerous small holes for liquid particles to pass through, while larger solid particles cannot pass through. ; Filter paper is used for the separation of liquid and solid substances, and can be used to pack pickles in the packaging, and soluble filter paper is used to prepare paper-shaped sheets.
Blow molding is often used for hollow plastic containers. Blow molding is divided into injection blow molding and extrusion blow molding. Injection blow molding is to inject molten plastic into the injection film to form a tube blank, and then close the blown film to pass The core film is blown into compressed air, and the parison is inflated to form a hollow container. This method is suitable for small and delicate plastic bottles; extrusion blow molding is to continuously add multiple blown films to the tube blank extruded by the extruder, and blow them separately. Enter compressed air to form a hollow container, and cool it to obtain a finished product. The extrusion blow molding method is suitable for preparing large containers. The tube blank formed by injection blow molding and extrusion blow molding is first stretched longitudinally with an extension rod, and then compressed air is introduced for inflation. The technique to achieve transverse stretching is called stretch blow molding. The production methods of plastic film include extrusion method and calendering method. The extrusion method can be divided into the blow molding method using a round head and the casting method using a slit head. The calendering method is to mix the prepared The softened plastic plasticized by the machine is sent to a calender with heated multi-roll rollers for calendering, and then cooled on a cooling roller to produce thin or slightly thicker films. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for pharmaceutical packaging material dust-free workshops and purification workshops, with professional technology, rich experience, affordable prices, and many successful cases.
Glass has stable performance and is an excellent packaging container, but its biggest disadvantage is that it is fragile; the research on the compatibility of glass containers with drugs should focus on the migration of metal ions in glass components into the liquid, and the leaching amount of harmful substances in glass containers should not be Exceeding the safe value, the leaching amount of various ions should not affect the quality of the drug. For example, the leaching of alkali metal ions should not cause changes in the pH value of the drug solution; evaluate the degree of danger that may be caused by glass peeling and non-visible and visible glass particles. Check that the glass container can withstand the action of the packaged material to ensure that the inner surface structure is not damaged during the storage of the medicine. The composite material is a material composed of two or more different materials. The composite material improves the performance of a single material and can give play to the advantages of each combined material. Both films and plastic bottles can be composited. The composite material composed of paper and polyethylene Film, which can be written as paper/PE, the former represents the outer layer, providing tensile strength and printing surface, and the latter represents the inner layer, providing barrier properties and heat sealing properties. Commonly used packaging techniques include moisture-proof packaging, shading packaging, heat shrink packaging, safety packaging, etc.
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