Aerosol potting GMP workshop
Aerosol potting GMP workshop
Aerosol encapsulation is mainly used for enterprise aerosol encapsulation production, suitable for food, chemical and other fields, such as air fresheners, cleaning agents, etc. Machines, cartoning machines, etc.; the loading capacity of the pharmaceutical industry is generally 10-100ML, which are basically used...
Text label: aerosol potting and sealing GMP pharmaceutical cleanroom, clean pharmaceutical cleanroom design and construction, Zhongjing global purification
Aerosol Potting GMP
Aerosol encapsulation is mainly used for enterprise aerosol encapsulation production, suitable for food, chemical and other fields, such as air fresheners, cleaning agents, etc. Machines, cartoning machines, etc.; the filling capacity of the pharmaceutical industry is generally 10-100ML, which is basically packaged by aluminum filling bottles, and the filling and sealing equipment linkage line mainly consists of round aluminum filling bottles, spray pumps, spray valves, and outer covers. ; Aerosol linkage filling and sealing linkage line is composed of mesh belt bottle feeding machine, bottle blowing machine, filling and capping machine, tank gas machine, water bath leak detector, valve adding and capping machine, auxiliary material liquid buffer tank, weighing machine. Heavy-duty detectors, inkjet printers and other equipment; generally use a large-capacity mesh belt type bottle loading table, and manually load the bottles into the mesh belt. Depending on the bottle type, you can also use a turntable bottle feeder to arrange the bottles in single or double rows. The filling machine ensures that the bottles are discharged in an orderly manner, and the bottles are not poured.
Peristaltic pump or ceramic plunger pump is positioned in the bottle control plate and filled intermittently, and the liquid medicine is poured into the bottle quantitatively. If there are special needs, nitrogen protection can be implemented before and after filling; generally, centrifugal lifting is used. The pump head is straightened and sent out according to the requirements; the special deviation correction mechanism and the pump head addition method are adopted to overcome the influence of the bending and inclination of the suction pipe and ensure the successful pass rate of adding the pump head, because the suction pipe is larger than the bottle body The size is long, and it is necessary to overcome the skewing of the top of the pump head in the neutral area in front of the jet pump after adding the jet pump, resulting in the inability to fasten the pump head and leakage; there are two ways to roll the jet pump. , and the second is a small-bore bottle, with an externally closed type flower cover. The recovery system generally adopts the method of negative pressure to suck the leaked waste gas away and discharge it straight out of the room to ensure safe production; the perfusion system adopts the constant volume increase technology, positioning and intermittently injecting the propellant in the bottle control tray, and passing the propellant through the small The constant pressure and quantitative cans of the nozzle are put into the bottle; the drying system uses hot air to dry the water vapor in the groove of the bottle mouth and the bottle body, and the temperature and pressure are adjustable and kept constant; the valve and cover systems generally use electromagnetic oscillators to dry the spray valve, The outer cover is sorted and conveyed upright, and sent to the predetermined valve and cover station; the intermittent pressurized spray valve and the pressurized outer cover are positioned in the bottle control tray, and the double-head installation is generally used to ensure the pass rate and production capacity. . Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for GMP workshops and GMP workshops.
The installation layout requirements of the aerosol potting linkage line in the GMP workshop are as follows: a separate room is set up for the layout and installation of multiple rooms in the whole line; the line pipes are generally routed from the mezzanine at the top of the room, hanging down to the designated pre-point of the equipment, and the power supply Lines, air pressure pipelines, etc. are covered with stainless steel pipes and then extended into the purification area. If they can only be entered from the side wall, they can only be routed against the ground, but a protective bracket cover must be installed. Pre-shift inspection and maintenance must be done well, such as tightening, lubrication, alignment, etc., and focus on inspection of various safety protection measures, such as clutches, protective covers, emergency stop switches, etc.; Correct placement.
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