Layout of exhaust vents and exhaust ducts in GMP workshop
Layout of exhaust vents and exhaust ducts in GMP workshop
The air outlet in the GMP pharmaceutical cleanroom is used to discharge heat, moisture and pollutants. When the heat generated by the indoor equipment is too large, in order to save energy, the heat generated by the equipment can be discharged on the spot to reduce the cooling of the air conditioner. load, the position of the air outlet at this time should be set directly above the heat-generating equipment; if...
Text label: GMP workshop exhaust arrangement, GMP workshop exhaust duct setting
The layout of the exhaust port and exhaust pipe in the GMP workshop
The air outlet in the GMP workshop is used to discharge heat, moisture and pollutants. When the heat generated by the indoor equipment is too large, in order to save energy, the heat generated by the equipment can be discharged on the spot to reduce the cooling of the air conditioner. At this time, the exhaust port should be located directly above the heat generating equipment; if some wet surfaces cannot be sealed due to process requirements, in order to reduce the indoor humidity load, an exhaust hood can be set near the wet surface ; Harmful gases or particles may be emitted during the production process. The best pollution control method is to discharge pollutants in time at the pollutant emission source, which can be eliminated by measures such as exhaust hoods or airtight isolation hoods; for clean production workshops , It should be set flexibly according to the production process and equipment characteristics. If the process conditions allow, the effect of setting an exhaust hood is better than setting a top exhaust port to remove pollution, and setting a closed exhaust hood is better. When arranging the exhaust port, it should Comprehensive consideration of various regulations and production process conditions, determine the effective exhaust method and the location of the exhaust port.
After the location of the exhaust outlet and the exhaust method are determined, the exhaust duct system should be designed, and the exhaust system should be set up in each clean room of the GMP workshop alone or in parallel in multiple clean rooms, in addition to strictly implementing the relevant specifications In addition to the regulations, the system form should also be determined by analyzing the nature of the pollution; if the pollutants discharged in the production pharmaceutical cleanroom are of a uniform nature, they will not cause cross-contamination, and there will be no problems after mixing, and multiple clean rooms can be used. Share one exhaust system, the exhaust outlet of each exhaust system should directly lead to the outside, and should not be discharged into the ceiling interlayer; when the exhaust air contains corrosive substances, the exhaust pipe should be made of corrosion-resistant materials ; In the exhaust system, the pipes and exhaust hoods exposed to the clean room should be made of stainless steel plates, and the concealed pipes in the interlayer or in the channels can be made of galvanized steel plates or other plates that meet the exhaust requirements. The exhaust system of the GMP workshop should prevent the backflow of the outdoor air flow. The anti-backflow measures often taken in the project are: use a medium-efficiency or high-efficiency filter, because it not only has a filtering function, but more importantly, the wind pressure or heat pressure is unlikely to overcome the filter. Therefore, it is unlikely that the reverse air flow will be formed; however, when this measure is adopted, the filter needs to be cleaned and replaced regularly, otherwise the exhaust air volume will be affected. A check valve can also be used to prevent backflow, which is easy to use and does not require frequent maintenance and management, but the effect is not very good, because the sealing performance of the check valve is poor, and under the action of hot pressure or wind pressure, the outdoor airflow can easily penetrate into the indoor pollution clean room; Measures can be taken to prevent backflow by installing an electric sealing valve. As long as the quality of the sealing valve is good, the possibility of preventing outdoor pollution is high. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for GMP workshops and GMP workshops.
GMP pharmaceutical cleanroom When the exhaust system contains water vapor and condensable substances, a slope and a discharge port should be set in the exhaust system; when arranging the exhaust ducts, the principles of short, straight and smooth should be followed to minimize the Pipe fittings to reduce the resistance of the duct system, rain-proof louvers or rain-proof caps should be installed at the outlet of the exhaust system; when the exhaust air contains allergenic substances or harmful substances, it should be treated, which can be installed at the entrance of the exhaust system Install high-efficiency filters to prevent environmental pollution; for example, in experimental animal rooms, the harmful substances in the exhaust air are mainly odors such as ammonia, and measures can be taken to install activated carbon filters in the exhaust system to prevent odor pollution. .
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