GMP workshop fluidized bed dryer
GMP pharmaceutical cleanroom fluidized bed dryer
Fluidized bed dryer is a convective dryer that exchanges heat with heat-carrying gas in a fluidized state. Fluidized bed dryer uses hot air flow to make granular or The powdery wet material is in a boiling state to achieve the purpose of drying. When boiling and drying, the hot air ...
Text label: GMP plant equipment, fluidized bed dryer, Zhongjing Global Purification
GMP Plant Fluidized Bed Dryer
Fluidized bed dryer is a convective dryer that exchanges heat with heat-carrying gas in a fluidized state. Fluidized bed dryer uses hot air flow to make granular or The powdery wet material is in a boiling state to achieve the purpose of drying. During boiling drying, the flow rate of the hot air is kept between the critical fluidization speed and the take-out speed of the particles. The stagnant layer almost disappears, the contact area between the airflow and the particles is large, the volume heat transfer coefficient can reach 2.3-7kw/(m3.k), and the residence time of the material in the boiling dryer can be controlled. Advantages of fluidized bed dryer: uniform temperature and easy control; good heat transfer effect; high degree of product drying; sealing operation; Poor drying effect.
The boiling dryer is mainly used for the drying of materials with a diameter of 0.03-6mm. If the material particles are too small, it is easy to generate channel flow or be entrained. -5%, granularity is 10%-15%, according to the structure, the fluidized bed dryer can be divided into: single-layer cylindrical fluidized bed dryer, multi-layer fluidized bed dryer, horizontal multi-chamber fluidized bed dryer Dryer, Vibrating Fluid Bed Dryer, Enhanced Boiling Dryer, Inert Particle Fluid Bed Dryer, Spray Fluid Dryer. Single-layer cylindrical fluidized bed dryer, the wet material is sent into the dryer from the feeder, the air is filtered by the filter and then sent to the air heater for heating by the blower, and the hot air enters the fluidized bed through the bottom distribution plate, and the dried The material is discharged from the discharge pipe, and the air from the fluidized bed is evacuated by the cyclone to recover the entrained fine powder and then evacuated by the fan; when the drying is required to be uniform, a higher bed is required and the thermal efficiency is low, so it can be used for Products with large processing capacity and less stringent drying requirements are especially suitable for drying that only requires surface moisture removal. In order to overcome the disadvantage of the unevenness of the single-layer fluidized bed dryer, a multi-layer fluidized bed dryer is designed. The wet material is added from the top layer, the hot air is fed from the bottom of the device, and the reverse flow is carried out in the bed layer. The first layer flows to the second layer through the overflow pipe. Although the particles are mixed with each other in the first layer, the layers are not mixed, so the drying degree of the product can be significantly improved, and the heat utilization rate is also higher than that of the single-layer fluidized bed. It is also possible to use no overflow pipe, and let the material flow directly from the larger diameter sieve plate hole to the lower layer to form a flow-through plate type, but the operation is not easy to master. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for GMP workshops and GMP workshops.
In order to overcome the shortcomings of the multi-layer fluidized bed, such as complex structure, large bed resistance, and difficult operation, a horizontal multi-layer fluidized bed dryer has emerged. It is a rectangular box shell, and its gas distribution The plate is rectangular, and a certain number of baffles are arranged perpendicular to it at certain intervals to separate the bed into multiple chambers; in order to make the gas distribution more uniform, there is generally a gas pre-distribution chamber at the lower part of the gas distribution plate, which is divided into several With a hot air chamber, the residence time of the material can be realized by adjusting the height of the outlet weir plate. Under the action of the hot air, the particles move to other chambers through the gap between the distribution plate and the partition plate until the outlet is discharged; and the multi-layer fluidized bed In comparison, the structure is simple, the system pressure is reduced, the unit air consumption is large, and the thermal efficiency is low. For paste-filled materials, in the past, box-type dryers were often used for drying, resulting in uneven product quality, poor operating conditions, high labor intensity, and low thermal efficiency. Solve the drying problem of paste-like materials; the enhanced boiling dryer has high thermal efficiency, high drying strength, good quality, low cost and stable operation. Spray fluidized drying is a method of combining the spray device of the solution in a gas-solid fluidized bed to fluidize and dry the droplets to obtain dry solid particles; the material solution is atomized by a nozzle into extremely fine droplets and dispersed in the bed layer, It can be dried into small particles by itself or covered on other small particles as seeds to grow up; spray fluidized drying can combine evaporation, crystallization, granulation, drying, etc. in one equipment, which can simplify the process and save investment, but There are problems such as high return ratio and energy consumption.
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