Precautions for selection of purification air conditioning system in sterile workshop

Precautions for selection of purification air conditioning system in sterile workshop

Aseptic workshop circulation system, the efficiency of the final filter in a system should be similar, which mainly considers the resistance balance of the system. If the resistance difference between the high-efficiency and medium-efficiency air purification systems is too large, the resistance is difficult to combine into one system. Balanced; if each filter actually...

Text label: sterile workshop design, sterile pharmaceutical cleanroom engineering, purification air conditioning system selection

Aseptic workshop purification air conditioning system selection considerations

Aseptic workshop circulation system, the efficiency of the final filter in a system should be similar, which mainly considers the resistance balance of the system. If the resistance difference between the high-efficiency and medium-efficiency air purification systems is too large, the resistance is difficult to combine into one system. Balance; if the actual air volume of each filter is very different, with the operation of the system, the resistance growth rate of each filter is also different, which may lead to system imbalance; the process requirements in the one-way flow sterile workshop are precise, and there are few indoor personnel. The process itself often does not generate much heat. In order to achieve a high degree of cleanliness, a large number of air changes is required, so that the temperature difference between the air supply in the one-way flow clean room is small. If the air is treated according to the requirement of small supply air temperature difference, it cannot meet the requirement of large supply air temperature difference, which is uneconomical in operation and very troublesome in management; for high-efficiency filters, there is an inconsistent resistance growth rate. Always maintain the resistance balance in the initial state of the system, it is bound to add many air valves and adjust them continuously during operation, which is troublesome and economical; In the centralized purification air conditioning system, the two are not allowed to be classified as one system.

The maintenance of the positive pressure in the sterile workshop is caused by the unorganized leakage of the air volume between the supply and return air. From the perspective of system balance, the sum of these unorganized leakage air volumes and the system exhaust air volume is equal to the amount of fresh air entering the system; for the same system, the higher the maintained positive pressure value, the more air volume is required. Some industries have a large exhaust air volume, so the system needs to supplement a large amount of fresh air, which generally greatly exceeds the fresh air volume required by the sanitary requirements, which increases the burden of fresh air filtration and treatment. If the production process requires each small system to run at the same time, then the fresh air of the system can be processed centrally, and then sent to the air treatment box of each small system for further processing, so that the fresh air after centralized treatment has stable parameters and reduces the air treatment burden of each small system , which is conducive to stabilizing the air parameters in the sterile workshop and facilitates the centralized management of fresh air filters; the centralized fresh air treatment system is generally filtered by primary and medium-efficiency filters, and can be preheated or pre-cooled at the same time according to the location and energy conditions. ; Fresh air centralized treatment systems often use independent fresh air fans, which are supplied to each small system by pressing in, so that the fresh air volume of each system can be guaranteed, and it is also conducive to the distribution and adjustment of fresh air volume between systems, and it will not be affected by the primary and secondary return air volume of the system. Adjustment and other reasons, causing changes in fresh air volume. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for sterile workshops and clean rooms.

The fresh air volume of the purification air conditioning system is very large, and the air volume to maintain positive pressure in the fresh air volume must be guaranteed, but the actual exhaust air volume and the designed exhaust air volume are often very different. The stop or opening of the air device or the change of the air volume often causes the change of the indoor positive pressure value. In order to maintain the appropriate positive pressure in the room, the excess air volume is discharged by the pressure control device, and the waste is very large; The fresh air volume is connected with the exhaust device through the central control device, and the fresh air intake can be adjusted according to the actual exhaust air volume of the exhaust device to reduce the fresh air load. If a residual pressure valve is set, the residual pressure valve should be arranged in the clean air flow Downwind side; the air volume processed by the purification air conditioning system is large, and the temperature difference between the supply air is relatively small. If no harmful substances are produced during the production process, or the harmful substances can be effectively discharged through the local exhaust, the amount of fresh air should be guaranteed. and positive pressure conditions, try to use the return air, especially the one-way flow clean room system has a larger air supply, and the process must be a secondary return air system, and the secondary return air volume is large; if a semi-centralized system or a full Although the distributed system can avoid the round-trip transportation of a large amount of supply and return air, these air volumes must be provided by large fans or multiple fans placed indoors or adjacent rooms, and their noise and vibration must be handled well.

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