Causes and treatment methods of tablet weight out of tolerance in tablet press1
2023-08-28
Sz Pharma
183
Tablet weight tolerance refers to the variation in tablet weight beyond the pharmacopoeia-specified limits. 1. The particle size is unevenly distributed during the tableting process, and the particle flow rate is different, resulting in uneven particle size filled into the middle mold hole. If the amount of coarse particles is high, the tablet will be lighter with more fine particles. Film weight. Solution: Granules should be thoroughly mixed or sieved to remove excess fines. 2. If
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