What are the cost of the 100,000-level clean workshop and the main factors that affect the cost of the clean workshop?

by:PHARMA     2022-11-05
At present, a large part of high-precision and cutting-edge industries are inseparable from clean workshops, such as CCL circuit substrate copper clad laminates, PCB printed circuit boards, optoelectronic LCD screens and LEDs, power and 3C lithium batteries, and some pharmaceutical food, medical equipment industries, etc. . We have seen class 100,000 clean rooms in many places, and many clean room class requirements are basically within this range. So what are the cost of the 100,000-class clean workshop and the main factors that affect the cost of the clean workshop? Let's first understand the standards of the 100,000-class clean workshop: From the perspective of the number of air changes: 100,000 (100,000) class requires 18- 25 times, the air purification time should not exceed 40 minutes after complete ventilation. Various grades, including 100,000-level clean room cleanliness standards, refer to the following: ISO 14644 classifies the air cleanliness of clean rooms (areas) and related controlled environments according to the only indicator of suspended particle concentration, and only considers particle size limits (Lower limit) 0.1um~5.0um
A swarm of particles with a cumulative distribution in the range. According to the particle size, it can be divided into conventional particles (0.1um ~ 5.0um), ultrafine particles (<0.1um) and macroparticles (>5.0um). Air cleanliness classification standard: ISO14644-1 (international standard) The 100,000-level clean workshop standard is: 1. The maximum allowable number of dust particles (per cubic meter); The number of particles equal to or equal to 5 microns shall not exceed 20,000; 3. The maximum allowable number of microorganisms; 4. The number of planktonic bacteria shall not exceed 500 per cubic meter; 5. The number of sedimentary bacteria shall not exceed 10 per petri dish. Pressure difference: The pressure difference between clean workshops of the same cleanliness level should be consistent. The pressure difference between adjacent clean workshops with different cleanliness levels should be ≥5Pa, and the pressure difference between clean workshops and non-clean workshops should be ≥10Pa. (1) The cost of the 10,000-class clean workshop Generally speaking, the 100,000-class clean workshop is 1500~2000 yuan/㎡; the cost of the clean workshop test report (ie the cleanliness test report) issued by the clean inspector is 50 yuan/㎡. Specifically, it should be calculated according to the owner's needs/area/industry/cleanliness/total project. And the price is for reference only. The specific price also involves factors such as the industry area. It is necessary to survey the site before making a detailed quotation. (2) Factors affecting the cost of clean workshop Several major factors of cost 1. Space factor The space factor is composed of two aspects: workshop area and pharmaceutical cleanroom floor height, which directly affects the cost of interior decoration and enclosure: color steel plate partition wall and ceiling area. The input cost of the air conditioner, the area volume of the air conditioner load required, the air supply and return mode of the air conditioner, the pipeline direction of the air conditioner, and the number of air conditioner terminals. To avoid the increase of project investment due to space reasons, the builders can comprehensively consider from two aspects: the working space of different production process equipment (including the height or width allowance for movement, maintenance and repair)
. The spatial trend of work flow and logistics. At present, the building follows the principles of saving land, materials and energy saving, so the bigger the clean workshop is, the better. When preparing for the construction, we should consider our own production process pharma machinery and processes, which can effectively avoid unnecessary investment costs. 2. Temperature, humidity and cleanliness factors Temperature, humidity and cleanliness are workshop environmental standard data tailored for industrial products, the highest design basis for clean workshops, and an important guarantee for product qualification rate and stability. The current standards are divided into national standards, local standards, industry standards, and enterprise internal standards. Such as cleanliness grade classification standards, pharmaceutical industry GMP standards, etc. belong to the national standard. For most manufacturing industries, the standard of clean workshop for each production process is determined mainly based on product characteristics. For example, the exposure, dry film, and solder mask temperature and humidity in the PCB industry are at 22+1°C, 55+5%
, The cleanliness ranges from one thousand to one hundred thousand. The lithium battery industry pays more attention to low humidity control. Generally, the relative humidity is below 20%. Some quite strict liquid injection workshops need to be controlled at about 1% relative humidity. Defining environmental data standards for clean workshops is the most crucial central point affecting project investment. The formulation of the cleanliness level affects the decoration cost: it is set at the level of 100,000 and above, which requires the necessary clean sheet enclosures, purification of doors and windows, air shower transfer facilities for personnel and goods, and even expensive raised floors. At the same time, it also affects the cost of air-conditioning: the higher the cleanliness, the greater the number of air-conditioning ventilations necessary for purification, the greater the air volume required for the purification air cabinet, and the volume of air ducts and high-efficiency air outlets at the end will also increase. In the same way, the formulation of temperature and humidity in the pharmaceutical cleanroom not only has the above-mentioned cost problems, but also the factors of control accuracy. The higher the accuracy, the more complete the supporting equipment required. If the relative humidity range is accurate to +3%, ±5%, the required humidification equipment and dehumidification equipment should be complete. The establishment of temperature, humidity and cleanliness of the workshop not only affects the initial investment, but also the operating cost in the later stage for a factory with a long-term foundation. , Reasonably formulating environmental data standards that meet their own needs is the most basic and fundamental step in preparing for the construction of a purification plant. 3. Other influencing factors In addition to the two major requirements of space and environment, some factors that affect the compliance of clean workshops are often ignored by designers or builders, resulting in excessive temperature and humidity. For example, the external climate is not considered comprehensively, the exhaust volume of the equipment is not considered, the calorific value of the equipment is not considered, the dust production of the equipment is not considered, and the humidity production of a large number of people working at the same time is not considered.
CUSTOM SOLUTION SERVICES are all following the most compatible manufacturing regulations.
Our knowledgeable loss prevention experts can help commercial customers reduce losses in CUSTOM SOLUTION SERVICES.
Our company specializes in manufacturing CUSTOM SOLUTION SERVICES mainly extraction machine.
SUZHOU PHARMA MACHINERY CO.,LTD. emphasizes our commitment to quality in our laboratory and R&D services.
Custom message
Chat Online
Chat Online
Leave Your Message inputting...
Sign in with: