The dust problem of domestic tablet presses needs to be solved urgently

Tablet presses are an indispensable piece of equipment for the pharmaceutical industry. It can compress all granules or powders and other irregular-shaped drugs into tablets to meet the needs of the modern drug market, so it is widely used in the pharmaceutical industry.

Among the many types of tablet presses, most pharmaceutical companies prefer rotary pharmaceutical tablet presses because it can not only ensure output, but also take into account quality and scale production. However, what troubles many pharmaceutical companies is that the rotary tablet press always has problems such as dust, drill punches, and differences in tablet punches during operation.

There is a dust problem in the tablet press process, which is an urgent problem to be solved. At present, the dust generated during the production and operation of domestic high-speed rotary tablet presses and tablet sieves is usually sucked out by using a special vacuum cleaner to provide negative pressure. However, due to the gap in the existing technical level and awareness, the sealing effect of the equipment itself is not ideal, and some dust still leaks into the purification area. In addition, the dust generated during the process of material transportation or tablet transfer may also leak directly to the purification area from the relevant joints.

Most of the tablet presses used by small and medium-sized pharmaceutical companies still have problems, such as contamination of the tablet machine, difficulty in cleaning, online testing of products, and manual filling of equipment operation records. Due to the limitations and defects of the equipment, it also brings many practical problems to the GMP management and product quality of the enterprise.

One of the main reasons for the pollution of the tablet press is that the design of the lubrication system is unreasonable, and the particularity of the pharmaceutical pharma machinery is not fully considered. A large number of liquid lubricants are used for the lubrication of the pharma machinery, and the sealing is not good, which often causes drug pollution. manufacturers can consider adding grease timing lubrication devices or adopting reliable sealing methods on the tablet press to reduce or eliminate the pollution of lubricants to drugs. Another major source of pollution is that the seal between the feeder and the rotary platform is not good, resulting in dust pollution. British MANESTY adopts a gapless feeder with a polyurethane sealing ring structure, so that the bottom of the feeder and the middle mold of the turntable can achieve zero-gap contact, which avoids the current sealing defects of the feeder.

Most of the domestic tablet pressing equipment is very difficult to clean and cannot be cleaned online. When cleaning, not only the upper punch, lower punch, and middle mold must be removed, but also there are many dead corners that are not easy to remove and clean. Some foreign tablet presses can realize fast loading and unloading and online cleaning. That is, with a few tools and a few adjustments, the parts that need to be cleaned can be assembled and disassembled quickly and conveniently. Some tablet presses also use interchangeable turntables for quick cleaning. Domestic tablet presses should also be improved in this regard.

The main development direction of foreign tablet presses: production under intelligent and ultra-micro unit control and sealing conditions. Some even use transmission equipment such as magnetic powder clutches and magnetic powder brakes, which shows that foreign tablet presses have gone a step further.

China's tablet press manufacturers should change the status quo of weak basic research and lack of talents, strengthen technological upgrading and perfection of innovation mechanisms, narrow the gap with foreign products, and effectively solve the dust problem.

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