Sterilization in purification workshop
Sterilization in purification workshop
Moist heat sterilization is a method of sterilizing with saturated steam, boiling water or circulating steam. High temperature and high pressure steam is used as the medium. Due to the large latent heat of steam and strong penetrating power, it is easy to denature or solidify proteins. The most commonly used sterilization method in the process; moist heat sterilization can be divided into...
Text label: sterilization treatment in purification workshop, design and installation of purification pharmaceutical cleanroom
Sterilization treatment in purification workshop
Moist heat sterilization is a method of sterilizing with saturated steam, boiling water or circulating steam. High temperature and high pressure steam is used as the medium. Due to the large latent heat of steam and strong penetrating power, it is easy to denature or solidify proteins. The most commonly used sterilization method in the process; moist heat sterilization method can be divided into boiling sterilization method, pasteurization method, high pressure steam sterilization method, circulating steam sterilization method and intermittent steam sterilization method; circulating steam sterilization method is Under normal pressure conditions, it is heated by circulating steam at 100°C, and the sterilization time is usually 30-60min. This method is suitable for sterilization and sterilization of heat-labile preparations. The intermittent steam sterilization method uses repeated circulating steam heating to kill all microorganisms, including spores. The method is the same as the circulating steam sterilization method, but it needs to be repeated more than 3 times. ℃ incubator overnight, the purpose is to make the spores develop into propagules. If the sterilized object is not resistant to high temperature of 100 ℃, the temperature can be lowered to 75-80 ℃, the heating time can be extended to 30-60min, and the number of times can be increased.
The high pressure steam sterilization method is 103.4KPa, the steam pressure temperature reaches 121.3℃, and it is maintained for 15-20min. If it is a spore-producing microorganism, it should be cultured at a suitable temperature for several hours after sterilization, and then sterilized again. Dry heat sterilization equipment is divided into intermittent dry heat sterilization equipment, continuous dry heat sterilization equipment, including hot air parallel flow, namely electrothermal laminar flow dry heat sterilization machine and far-infrared heating sterilization; Bacteria equipment is a method of killing microorganisms by using high-pressure water steam in an autoclave. There are many types of sterilizers for autoclaving. Most of them are devices that use electric heating wires to heat water to generate steam and maintain a certain pressure. It is mainly composed of a sealable barrel, pressure gauge, exhaust valve, safety valve, electric heating wire, etc.; according to the size, it can be divided into portable autoclave, vertical pressure steam sterilizer and horizontal type High-pressure steam sterilizers, etc.; vertical high-pressure steam sterilizers are available from 30-200L, each with the same volume is also divided into handwheel type, flip type and intelligent type, and intelligent type is divided into standard configuration, steam inner discharge And vacuum drying type, can also be equipped with a printer according to customer requirements, as well as a large horizontal autoclave. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for purification workshops and clean workshops.
Microwave sterilization is a method of killing microorganisms and spores by using the heat energy generated by microwave irradiation. It is suitable for the sterilization of liquid and solid materials, and has a drying effect on solid materials. In the deep part, the medium and the material can be heated uniformly inside and outside, and it has the advantages of low temperature, normal pressure, high efficiency, fast speed, low energy consumption, easy operation, easy maintenance, and long product shelf life. Ethylene oxide sterilization device is the key equipment for disposable sterile medical device manufacturers, and has special requirements for installation, operation and use management; ethylene oxide sterilization can destroy all microorganisms, including bacterial spores, and sterilized items can be It is wrapped and encapsulated as a whole, and it can be kept in a sterile state before use. Relatively speaking, ethylene oxide does not corrode plastics, metals and rubber, and will not make items yellow and brittle, and can penetrate irregularly shaped items and sterilize them. .
SUZHOU PHARMA MACHINERY CO.,LTD. have now make a decision to enlarge our company in other countries.
If you are interested in any of CUSTOM SOLUTION SERVICES, please feel free to contact us.
To stay in contact for latest review of CUSTOM SOLUTION SERVICES extraction machine across the globe and find out quality products, just go to PHARMA MACHINERY.
[拓展名称] include a great variety of devices with a wide range of complexity: from simple extraction machine used since prehistoric times to the complex of modern mechanized extraction machine.