Reasons and solutions for tablet machine splits
2023-01-05
Sz Pharma
204
The characteristics of the raw material itself, especially the crystal form. The cohesiveness of the material and the restoring force of the elastic deformation momentarily exceed the binding force between the particles, resulting in splits. The compressibility of the prescription, the compressibility of the prescription is not good, will lead to insufficient hardness of the tablet, if the pressure is increased blindly to increase the hardness in this case, not only the hardness will not increase, but also capping will appear.
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