Reasons and solutions for insufficient hardness of tablets pressed by tablet press
2023-09-27
Sz Pharma
183
In the daily operation of the tablet press machine, it is inevitable that the pressed tablets are not hard enough, which is a very distressing thing. Let us analyze the reasons and solutions for the hard pressing. (1) Reason: The amount of binder or lubricant is small or inappropriate, resulting in uneven distribution of particles, stratification of coarse and fine particles, which cannot be overcome even if the pressure is increased during tablet compression. Solution: choose appropriate binder or increase dosage, improve granulation process,
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