Focuses On Professional Cleanroom Project And Pharmaceutical Cleanroom Equipment.
Causes and treatment methods of tablet press sticking: Sticking is the adhesion of fine powder to the surface of the tablet through the punch and die, which not only causes unevenness on the surface of the tablet, but also causes unevenness. . Lettering punches are easier to stick.
1. Insufficient amount of lubricant or improper selection and too much fine powder. Appropriately increase the amount of lubricant in the tablet press or replace with a new lubricant to remove excess fine powder.
2. The engraving and punching character design is unreasonable. Replace the hole punch or change the character design accordingly.
3. The water content of the granules is too much or the granules are not dry and moist, resulting in adhesion. Solution: Control the moisture content of granules within the range of 2%~3%, and strengthen the inspection of dry food.
4. Adhesion caused by the raw material itself (such as hygroscopicity). Solution: Add a certain amount of absorbent (such as adding 3% calcium hydrogen phosphate) to avoid adhesion.
5. The fineness of raw and auxiliary materials varies greatly, resulting in uneven mixing or inappropriate mixing time. Solution: crush and sieve the raw and auxiliary materials to make the fineness meet the quality requirements of the variety, master and control the mixing time.
6. Due to the quality of the adhesive, the adhesive concentration is low or the adhesion is poor. Too much fines (more than 10%) and sticking. Solution: The fine powder is sieved through a 40-mesh sieve, granulated again, dried and granulated, the whole batch is mixed evenly, and then compressed into tablets.
7. The surface of the punch is damaged or the surface finish is reduced. There may also be anti-rust oil or lubricating oil, the surface of the new mold is rough or the lettering is too deep and angular. The punch can be wiped clean and replaced with a substandard mold, or rubbed with a small amount of liquid paraffin on the surface of the lettering punch to lubricate the surface. Also, if the sticking is caused by mechanical heating, check the cause and repair the device.
8. The ambient humidity is too high and the humidity is too high. Reduce ambient humidity.
9. The operating room temperature of the tablet press is too high, which is easy to produce viscous punches. Attention should be paid to reducing the operating room temperature.