Clean laboratory air supply ventilation and exhaust system
Clean laboratory air supply ventilation and exhaust system
In the analysis work of the clean laboratory, the instruments and equipment need to use various gases, including the carrier gas for chromatographic analysis. In the construction of the laboratory, it is important to consider the construction of the gas source room and the laying specifications of the gas transmission pipeline; the gas source For gas cylinders, cryogenic liquid cylinders or gas...
Text label: clean laboratory system, air supply ventilation and exhaust system, laboratory installation
Clean Laboratory Air Supply Ventilation and Exhaust System
In the analysis work of the clean laboratory, the instruments and equipment need to use various gases, including the carrier gas for chromatographic analysis. In the construction of the laboratory, it is important to consider the construction of the gas source room and the laying specifications of the gas transmission pipeline; the gas source For gas cylinders, cryogenic liquid cylinders or gas generators, gas cylinders must be placed in a cool, dry room away from heat sources. Depending on the type of gas, gas cylinders should be stored in different rooms; For the ventilation measures of 3 times of ventilation, the cylinder room is generally built beside the laboratory building. The gas supply in the laboratory should be different from the requirements of the general pharmaceutical cleanroom. There are strict regulations from the initial design and construction to the pressure-holding test after the final installation. First of all, the instruments and equipment have very high requirements on the purity of the gas. It is required to reach more than 99.999%. Secondly, the supply of gas must be continuous and uninterrupted, and the output pressure must be stable. If the gas pressure occurs, it may lead to unstable operation of the equipment; discontinuous supply of gas and insufficient pressure are more likely to cause equipment failure. Therefore, the design of laboratory gas pipelines must be very strict.
The composition of the central gas supply pipeline includes the origin system, switching system, piping system, pressure regulating system, emergency cut-off system; generally nitrogen or other inert gas is checked, non-high pressure pipelines must be tested under a pressure of not less than 106pa, Before the test, the pipeline to be tested must be marked and isolated from the pipeline valve; before the pressure test, the test pressure must be 1.2 to 1.5 times the working pressure, and the time is 30 minutes to observe whether the pressure drops abnormally; during the pressure drop test, slowly Increase the pressure of the gas in the pipeline. When the required pressure is reached, close the valve and keep it for 24H, and observe whether there is any abnormal pressure and drop. The laboratory ventilation and exhaust system includes natural ventilation, mechanical ventilation, and local exhaust air; natural ventilation utilizes the temperature difference between indoor and outdoor, that is, the heat pressure generated by the density difference between indoor and outdoor air, and discharges harmful indoor gases to the outdoors. For rooms with low concentrations of harmful substances, it is suitable for occasions where the indoor temperature is higher than the outdoor air temperature. The upper and lower air inlets should be designed in the laboratory. Zhongjing Global Purification can provide consulting, planning, design, construction, installation, transformation and other supporting services for clean laboratories and sterile laboratories.
When natural ventilation cannot meet the requirements of indoor ventilation, mechanical ventilation should be used. For rooms that emit corrosive gases, such as acid warehouses, axial flow fans should not be used. Local exhaust, generally including fume hood exhaust, universal exhaust hood exhaust, desktop ventilation hood exhaust and so on. The operating wind speed of the fume hood is one of the key issues for the emergency and rational use of the fume hood; for some instruments and equipment that generate exhaust gas, such as gas chromatographs and liquid chromatography tandem mass spectrometers, special pipes should be considered for the exhaust gas discharged when the instruments are running. The laboratory lighting system should be equipped with a separate power supply device or loop power supply, and separate switches and protective appliances should be provided; the lighting distribution box should be set up separately for each laboratory; special laboratories should be equipped with emergency lighting devices.
There is a strong need for more research on , in order to be able to provide strong and conclusive evidence of their extraction machine effects. However, recent studies have provided valuable insights into how the intake of may result in improved extraction machine.
SUZHOU PHARMA MACHINERY CO.,LTD. seeks to lead the industry by instilling pride in our customers, creating value for the market and sharing responsibility around the world.
PHARMA provides a number of extraction machine designed to handle extraction machine.
In clean area management and quality control, laminar flow interference testing has received much attention, and whether it is only applicable to Class A laminar flow remains to be considered.